Novel Vascular Disrupting AgentsAre Coming of Age

OXiGENE is a clinical-stage biopharmaceutical company developing novel therapeutics to treat cancers, such as ovarian and certain thyroid cancers. The Company’s major focus is developing vascular disrupting agents (VDAs) that selectively disrupt abnormal blood vessels associated with solid tumors. OXiGENE is dedicated to leveraging its scientific expertise, intellectual property and therapeutic development capabilities to bring life-extending and life-enhancing medicines to patients.

New Phase 2 Study

Learn about a new Phase 2 study evaluating fosbretabulin as a treatment for gastrointestinal neuroendocrine tumors, or GI-NETs.

GI-NETs are slow-growing tumors that can spread and produce debilitating symptoms, including episodic flushing, diarrhea, wheezing, and the eventual development of carcinoid heart disease.

Compelling Pipeline

After many years of research, we believe that fosbretabulin is poised to become the first commercialized VDA, having shown meaningful clinical activity and tolerability in clinical trials to date.

Click here to see our diverse pipeline.

About VDAs

Vascular Disrupting Agents or “VDAs” block blood flow through established tumor blood vessels, thereby starving tumors of oxygen and essential nutrients, leading to tumor cell death.

Watch a video to learn more about this novel approach.