Novel Vascular Disrupting AgentsAre Coming of Age

OXiGENE is a clinical-stage biopharmaceutical company developing novel therapeutics to treat cancers, such as ovarian and certain thyroid cancers. The Company’s major focus is developing vascular disrupting agents (VDAs) that selectively disrupt abnormal blood vessels associated with solid tumors. OXiGENE is dedicated to leveraging its scientific expertise, intellectual property and therapeutic development capabilities to bring life-extending and life-enhancing medicines to patients.

About VDAs

Vascular Disrupting Agents or “VDAs” block blood flow through established tumor blood vessels, thereby starving tumors of oxygen and essential nutrients, leading to tumor cell death.

Watch a video to learn more about this novel approach.

Compelling Pipeline

After many years of research, we believe that ZYBRESTAT® is poised to become the first commercialized VDA, having shown meaningful clinical activity and tolerability in clinical trials to date.

Click here to see our diverse pipeline.

Ovarian Cancer: A Serious Unmet Need

Highly lethal ovarian cancer is responsible for the death of more than 14,000 women each year in the U.S. alone.

Click here to learn about ongoing clinical trials to evaluate ZYBRESTAT® in this patient population.